Evaluation the effect of ZIF-8 loading onto polyacrylonitrile membrane for separation of anti-cancer doxorubicin from synthetic wastewater
Volume Title: 1
Authors
1Department of Chemical Engineering, College of Engineering, University of Isfahan, P.O. Box 81746-73441, Isfahan, Iran
2Department of Chemistry, Isfahan University of Technology, Isfahan, Iran
Abstract
Nanoparticle addition to membranes is advancing the performance of separation processes and improving the flux without jeopardizing the selectivity. In this study, interfacial polymerization synthesis method was used to create a uniform layer of zeolitic imidazolate framework-8 (ZIF-8) -as a pH sensitive nanoparticle- on the porous polyacrilonitrile (PAN) ultrafiltration membranes to separation of doxorubicin (DOX) from water. The filtration expriments showed that by loading 0.12 wt.% ZIF-8, the DOX rejection increases from 78% for PA/PAN membrane to 98% for ZIF-8-PA/PAN membrane which could be due to the decrease in the pores size of the membranes. By changing the pH from 2 to 8, for ZIF-8-PA/PAN membrane, DOX flux increased from 6.01 to 23.53 L/m2.h and then decreased at pH =10 to 7.51 L/m2.h. This can be due to the increase in the pores size from pH = 2 to 8 and then decrease in size to pH =10. Moreover, DOX rejection increased from 80% to 96% by changing in pH form 2 to 8 . This may be due to electrostatic repultion betweem DOX and membrane surface
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